HPE ProLiant DL380 Gen12 6517P Server
16‑core 3.20 GHz, 64GB RAM
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Overview:
Are you looking for a two-socket scalable server that powers data analytics and supports hybrid cloud workloads?
The HPE ProLiant Compute DL380 Gen12 is a scalable 2U 2P server that delivers exceptional compute performance, memory density with scalability and high-speed data transfer rate to run your most demanding applications. Powered by Intel® Xeon® 6 processors with up to 144 cores and up to 8 TB of memory as well as 36 EDSFF E3.S drives, the HPE ProLiant Compute DL380 Gen12 is an ideal hybrid cloud platform for enterprise applications and workloads.
The HPE ProLiant Compute DL380 Gen12 is engineered for your future, with next-level security, optimized performance and efficiencies, and automated, AI-driven productivity.
P89239-005 - HPE ProLiant Compute DL380 Gen12 server with one Intel® Xeon® 6517P Processor, 64 GB (2x32 GB) Dual Rank Memory, one HPE MR408i-o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller, one HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device, support for eight SFF drives, one HPE ProLiant DL380/DL560 Gen11 2U High Performance Fan Kit, two HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kits, one TPM (Trusted Platform Module), one HPE Bezel Lock Kit, one HPE ProLiant DL3XX Gen11 Intrusion Cable Kit, one HPE Gen11 2U Bezel Kit, and a 3/3/3 warranty.
What's New
- Intel® Xeon® 6 processors that support up to 144 cores, up to 8 TB of DDR5 memory at speeds up to 6400 MT/s, and up to 2x average higher performance for general compute versus previous generations.
- Optional front accessible boot device for quicker access.
- Choice of two cooling options — air cooling or direct liquid cooling (DLC) for performance and energy efficiency to support sustainability initiatives.
- Up to 36 EDSFF E3.S NVMe drives.
- Up to three double-wide (DW) or eight single-wide (SW) GPUs.
- HPE Integrated Lights-Out 7 (iLO 7) server management software with streamlined manageability through a redesigned GUI, Redfish API, and increased security via the patented secure enclave technology.
Features:
Next-Level Security
From silicon to software, from factory to cloud, and from generation to generation, HPE ProLiant Compute Gen12 is engineered with a fundamental security approach to defend against increasingly complex threats through an uncompromising commitment to constant security advancements built into our DNA.
With the silicon root of trust from HPE and a zero-trust security framework to help ensure firmware integrity, this server continuously detects if it is compromised and is prevented from booting if malicious code is found. Additionally, this server is safeguarded with default IDevID certificates.
HPE ProLiant Compute servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.
The HPE ProLiant Compute DL380 Gen12, powered by Intel® Xeon® 6 processors, adds hardware- and softwareassisted security features, including Intel® Software Guard Extensions (SGX) for application isolation and Trusted Domain Extensions (TDX) for VM isolation.
HPE iLO 7 supports quantum-resistant (PQC) algorithms and signs HPE ProLiant Compute Gen12 firmware with algorithms approved by CNSA 2.0, which enhances resilience against potential future attacks by quantum computers.
Optimized Performance for Your Workloads
An excellent choice for compute and data storage demanding workloads requiring maximum core count, GPU capabilities, and network and I/O bandwidth.
Powered by Intel® Xeon® 6 processors with next-generation technology including 16 DIMM channels per processor that supports up to 144 cores and up to 8 TB of DDR5 memory at speeds up to 6400 MT/s.
Advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 6 x16 PCIe Gen5 and 2 OCP slots to improve I/O throughput and reduce latency.
HPE iLO 7 provides real-time operational feedback on server performance plus recommendations for fine-tuning BIOS settings to customize for changing business needs.
Choice of two cooling options — air-cooling or direct liquid cooling (DLC) for performance and energy efficiency to support sustainability initiatives.
Automated, AI-Driven Productivity
HPE ProLiant Compute DL380 Gen12 servers power demanding workloads with the highest security standard for every stage of the server lifecycle, and visibility to drive energy usage and cost efficiencies, helping you optimize your business from edge to cloud.
Transform operations to do more, see more, and gain greater, more proactive control through AI-driven insights. Monitor and maintain all servers within your distributed environment with actionable dashboards that provide a clear view of up-to-date status of server health across all locations.
Automate tasks for efficiency in deployment, instant scalability, and seamless, simplified support and lifecycle management reducing tasks and shortening maintenance windows.
These experiences are engineered and built into all HPE ProLiant Compute Gen12 servers, whether purchased as physical servers or consumed as-a-service using HPE GreenLake as your compute and storage demands grow.
Simplify and secure server management from edge to cloud with HPE Compute Ops Management, an as-a-service compute management experience that delivers greater simplicity, agility, and speed across your distributed compute environment.
Technical Specifications:
| HPE ProLiant Compute DL380 Gen12 6517P 1P 2x32GB-R 8SFF NS204i-u v2 MR408i-o 2x1000W PS NA Server Specifications | |
|---|---|
| Product Number | P89239-005 |
| Processor name | Intel® Xeon® 6517P (16 core, 3.20 GHz, 72 MB L3, 190W) |
| Processor number | 1 processor included |
| Processor core available | 16 core |
| Processor cache | 72 MB L3 |
| Processor speed | 3.20 GHz |
| Memory type | HPE DDR5 Smart Memory |
| Included memory | 64 GB (2x32 GB, 6400 MT/s) |
| Accelerators | Optional |
| System fan features | 6x High Performance Fan |
| Expansion slots | Up to 8 PCIe Gen5, and 2 OCP 3.0 (front or rear), for detailed descriptions reference the QuickSpecs |
| Form factor | 2U Rack |
| Network controller | Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE |
| Storage controller | HPE MR408i-o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device |
| Included drives | None ship standard, 8 SFF supported |
| Optical drive type | Optional DVD-ROM Optional through Universal Media Bay External support only. |
| Power supply type | 2x HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit |
| Infrastructure management | HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, HPE OneView Advanced (optional, requires licenses), and HPE Compute Ops Management (optional subscription available) |
| Security | HPE TPM 2.0 standard on motherboard. Optional locking Bezel Kit, Intrusion Detection Kit. For full security features refer to the QuickSpecs. |
| Warranty | Server Warranty includes three years of parts, three years of labor, and three years of on-site support coverage. |
Hardware Specs:
HPE ProLiant DL380 Gen12 server

Front View –SFF CTO Server with optional multi-purpose cage
| 1. | Box 1 for 8SFF drives or Optional Universal Media Bay (ODD, DisplayPort and 2 USB 3.2 Gen1 Ports) with 2SFF drives, shown empty |
| 2. | Box 2 for 8SFF drives or optional multi-purpose cage (shown) |
| 3. | Optional 4 EDSFF drives (shown in multi-purpose cage in Box 2) |
| 4. | Optional front NS204i-u (shown in multipurpose cage in Box2) |
| 5. | Quick-removal access panel |
| 6. | Optional front Primary OCP Slot (shown in multi-purpose cage in Box 2) |
| 7. | Optional front Secondary OCP Slot (shown in multi-purpose cage in Box 2) |
| 8. | Unit identification button / LED |
| 9. | NIC status1 |
| 10. | Health LED |
| 11. | Power on / standby button / LED |
| 12. | USB-C iLO service port |
| 13. | USB 3.2 Gen1 Port |
| 14. | Box 3 for 8SFF drives (shown) |
| 15. | Drive support label |
| 16. | Serial number label pull tab |
Notes:1 Front NIC LED display doesn't support NIC LED ACT/LINK indication from PCIE NICs

Front View – 24 SFF CTO Server
| 1. | Box 1 for 8 SFF drives (shown) |
| 2. | Box 2 for 8 SFF drives (shown) |
| 3. | Quick-removal access panel |
| 4. | Box 3 for 8 SFF drives (shown) |
| 5. | Unit identification button / LED |
| 6. | NIC status |
| 7. | Health LED |
| 8. | Power on / standby button / LED |
| 9. | USB-C iLO service port |
| 10. | USB 3.2 Gen 1 port |
| 11. | Drive support label |
| 12. | Serial number label pull tab |

Front View – 8 LFF CTO Server with optional 2SFF and Universal Media Bay
| 1. | Optional 2 SFF drives in Box 1 |
| 2. | Quick-removal access panel |
| 3. | Optional ODD Kit in Box 1 (shown without the ODD) |
| 4. | NIC status |
| 5. | Power on / standby button / LED |
| 6. | Health LED |
| 7. | Power on / standby button / LED |
| 8. | USB-C iLO service port |
| 9. | USB 3.2 Gen1 port |
| 10. | Optional DisplayPort via ODD Kit in Box 1 (shown) |
| 11. | Box 2 and 3 for 4 LFF drives in each box (shown) |
| 12. | Drive support label |
| 13. | Serial number label pull tab |

Front View – 12 LFF CTO Server
| 1. | Quick-removal access panel |
| 2. | Unit identification button / LED |
| 3. | NIC status |
| 4. | Health LED |
| 5. | Power on / standby button / LED |
| 6. | USB-C iLO service port |
| 7. | USB 3.2 Gen1 port |
| 8. | Box 1, 2 and 3 for 4 LFF drives in each box (shown) |
| 9. | Drive support label |
| 10. | Serial number label pull tab |

Front View – EDSFF CTO Server
| 1. | Box 1 for 12 EDSFF drives or 8SFF drive (shown empty) |
| 2. | Box 2 for 12 EDSFF drives (shown) or multipurpose cage |
| 3. | Quick-removal access panel |
| 4. | Box3 for 12 EDSFF drives or 8SFF drives (shown empty) |
| 5. | Unit identification button / LED |
| 6. | NIC status |
| 7. | Health LED |
| 8. | Power on / standby button / LED |
| 9. | USB-C iLO service port |
| 10. | USB 3.2 Gen 1 port |
| 11. | Drive support label |
| 12. | Serial number label pull tab |

Internal View SFF chassis – Air Cooled
| 1. | Processors, heatsinks (shown) |
| 2. | Optional NS204i-u Boot Device |
| 3. | Hot Plug redundant HPE Flexible Slot Power Supplies |
| 4. | Secondary Riser (Optional-not shown, Requires second processor) |
| 5. | Primary Riser |
| 6. | DIMM slots, shown fully populated in 32 slots |
| 7. | Hot Plug Fans |
| 8. | Drive Backplanes |
| 9. | Drive Cages |

Internal View 12LFF Chassis – Direct Liquid Cooling
| 1. | Processors, heatsinks (shown) |
| 2. | Direct Liquid Cooling tubes (NS204i-u version) |
| 3. | Hot Plug redundant HPE Flexible Slot Power Supplies |
| 4. | Secondary Riser (Optional shown, Requires second processor) |
| 5. | Primary Riser |
| 6. | DIMM slots, shown fully populated in 32 slots |
| 7. | Hot Plug Fans |
| 8. | Drive Backplanes |
| 9. | Drive Cages |

Rear View – DL380 Gen12 Air Cooled
| 1. | Box 4 for Primary Riser (Default PCIe 5.0 Slots 1, 2 & 3) or optional 2 SFF drive & slot 3 or Optional 2 LFF |
| 2. | Box 5 for Secondary Riser (Optional PCIe 5.0 Slots 4, 5 & 6) or optional 2 SFF drives & slot 6 or Optional 2 LFF |
| 3. | Box 6 for Tertiary riser (slots 7 & 8) or optional 2 SFF |
| 4. | NS204i-u Boot Device (Optional) |
| 5. | Power Supply 1 & 2 |
| 6. | VGA Connector |
| 7. | OCP 3.0 Slot-B |
| 8. | Serial Port (Optional) |
| 9. | Dedicated iLO Management Port |
| 10. | USB 3.2 Gen 1 Connectors (2) |
| 11. | UID Indicator LED |
| 12. | OCP 3.0 Slot-A |

Rear View – DL380 Gen12 Direct Liquid Cooling
| 1. | Box 4 for Primary Riser (Default PCIe 5.0 Slots 1, 2 & 3) or optional 2 SFF drive & slot 3 or Optional 2 LFF |
| 2. | Box 5 for Secondary Riser (Optional PCIe 5.0 Slots 4, 5 & 6) or optional 2 SFF drives & slot 6 or Optional 2 LFF |
| 3. | Box 6 for Tertiary riser (slots 7 & 8) or optional 2 SFF |
| 4. | DLC Tubes (NS204i-u position) |
| 5. | Power Supply 1 (Blank shown for Power Supply 2) |
| 6. | VGA Connector |
| 7. | OCP 3.0 Slot-B |
| 8. | Serial Port (Optional) |
| 9. | Dedicated iLO Management Port |
| 10. | USB 3.2 Gen 1 Connectors (2) |
| 11. | UID Indicator LED |
| 12. | OCP 3.0 Slot-A |
Services & Add-Ons:
HPE Tech Care (Support Plans)
HPE Tech Care is an operational support service from HPE for hardware, software, and multivendor systems. It helps your systems run smoothly, improves reliability, and drives performance. Official HPE Tech Care Datasheet
- Hardware & software support from HPE experts
- Access via phone, email, chat & self-service tools
- Standard response times & on-site as per HPE availability
- General technical guidance for operations & management
- All features in Basic, plus faster response & support
- Enhanced phone response; quicker callback for severity-1 incidents
- Proactive technical guidance and more frequent advisory from HPE
- Self-serve tools and knowledge base + access to digital insights via HPE
| Feature | Basic | Essential |
|---|---|---|
| Hardware & Software Coverage | HPE-provided support for both hardware & software | Same, with faster response & enhanced assistance |
| Support Channels | Phone, email, chat, self-service tools | All channels + more aggressive response SLAs |
| Response Time | Standard response per HPE’s availability | Improved/faster response for high-severity issues (e.g. severity-1) |
| Proactive Guidance | General technical guidance | Extra guidance in usage, management, and performance opportunities |
HPE iLO Advanced (Remote Management)
HPE Integrated Lights-Out (iLO) Advanced unlocks secure, full-feature remote administration for HPE ProLiant servers—enabling setup, monitoring, troubleshooting, and power control from anywhere.
Key Capabilities
- Integrated Remote Console with virtual keyboard and mouse
- Virtual media & folders for remote OS/software installs
- Console record & playback for audit and troubleshooting
- Collaborative access for multiple administrators
- Power/thermal monitoring with history and dynamic capping
- iLO Federation group management (group media, power, licensing)
Security & Compliance
- Silicon Root of Trust and platform component integrity checks
- Directory integration and 2-factor authentication (CAC/PIV)
- Device identity (IDevID/LDevID) aligned with IEEE 802.1AR
- Kerberos-based single sign-on for streamlined access
| Feature | iLO Standard | iLO Advanced |
|---|---|---|
| Remote Console | Basic access | Full Integrated Remote Console with collaboration |
| Virtual Media | Limited | Virtual media & folders for remote installs |
| Recording | — | Console record & playback |
| Power & Thermal | Monitoring | Monitoring + history and dynamic power capping |
| Federation (Group Mgmt) | Limited | Group media, power control, power capping, license activation |
| Security | Baseline iLO security | Directory auth, CAC/PIV, Kerberos, device identities, silicon root of trust enhancements |
Microsoft Windows Server 2025 (ROK AMS Software)
Choose the right edition of Microsoft Windows Server 2025 to power your Smart Choice Servers and Storage. Each edition is tailored to different business sizes and virtualization needs.
Essentials10-Core
- Up to 25 users / 50 devices
- Simplified licensing for small businesses
- No virtualization rights
Standard16-Core
- For growing businesses
- Supports 2 virtual machines
- Full Windows Server feature set
Datacenter16-Core
- For enterprises & data centers
- Unlimited virtualization rights
- Advanced features for large-scale workloads
| Edition | Best For | Virtualization | Users / Devices |
|---|---|---|---|
| Essentials | Small businesses | None | 25 users / 50 devices |
| Standard | SMBs with moderate workloads | Up to 2 VMs | Licensed per 16-core base + CALs |
| Datacenter | Enterprises / virtualization-heavy environments | Unlimited VMs | Licensed per 16-core base + CALs |
HPE Storage Options
Choose the right storage for your Smart Choice Servers. HPE offers HDD, SSD, and SAS options, each with different balances of cost, performance, and reliability.
HDD Hard Disk Drive
- Large capacity, lower cost
- Slower performance
- Great for bulk storage & backups
SSD Solid-State Drive
- High performance, faster boot & apps
- Better for databases & OS
- Higher cost per GB
SAS Serial Attached SCSI
- Enterprise-grade reliability
- High performance for mission-critical workloads
- Designed for 24/7 operations
| Type | Best For | Performance | Cost |
|---|---|---|---|
| HDD | Bulk storage, backups | Slowest | Low |
| SSD | OS, applications, databases | High | Medium–High |
| SAS | Enterprise workloads, 24/7 uptime | Very High | High |
HPE Memory Options
Smart Choice Servers and Storage support DDR5 memory for improved performance, efficiency, and scalability. Choosing the right amount of memory ensures your workloads run smoothly, whether it’s databases, virtualization, or everyday applications.
16GB DDR5-4800
- Good for basic workloads & file servers
- Suitable for small office environments
- Entry-level performance
32GB DDR5-4800
- Ideal for virtualization, databases, and multitasking
- Supports more demanding business workloads
- Higher performance headroom
| Option | Best For | Performance | Scalability |
|---|---|---|---|
| 16GB DDR5-4800 | Entry workloads, file/print servers | Baseline | Limited |
| 32GB DDR5-4800 | Virtualization, databases, larger workloads | High | Better scalability with more DIMMs |
Quick Recommendations
To help you decide, we’ve put together sample configurations that match common business needs.
Small Office / Basic Workloads
- Support: Tech Care Basic (3Y)
- Remote Mgmt: Optional iLO Advanced
- OS: Windows Server 2025 Essentials
- Storage: HDD (affordable, large capacity)
- Memory: 16GB DDR5
Why: Essentials edition is perfect for ≤25 users, while 16GB RAM and HDDs keep costs low. iLO Advanced is optional if you don’t need remote management.
Growing Business / Virtualization
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced (3Y)
- OS: Windows Server 2025 Standard
- Storage: SSD (OS/apps) + HDD (data)
- Memory: 32GB DDR5
Why: Standard edition allows up to 2 VMs for growth. A mix of SSD + HDD balances performance and cost. iLO Advanced ensures remote management as IT expands.
Enterprise / Mission-Critical Workloads
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced with Federation
- OS: Windows Server 2025 Datacenter
- Storage: SAS drives (high reliability)
- Memory: 32GB+ DDR5 (expandable)
Why: Datacenter edition unlocks unlimited virtualization. SAS drives support 24/7 uptime, while more RAM ensures smooth performance across many workloads.
Branch Office / Remote Site
- Support: Tech Care Essential (3Y)
- Remote Mgmt: iLO Advanced (critical for remote access)
- OS: Windows Server 2025 Standard
- Storage: SSD for fast apps, small HDD for data
- Memory: 16GB or 32GB DDR5
Why: Remote management via iLO is vital since IT staff may not be on-site. Standard edition supports light virtualization or file/print roles for branch users.
Development / Test Lab
- Support: Tech Care Basic (1–3Y)
- Remote Mgmt: iLO Advanced (collaboration features)
- OS: Windows Server 2025 Standard
- Storage: SSD-heavy (fast rebuilds)
- Memory: 32GB DDR5
Why: Developers benefit from iLO’s remote console recording/playback and SSD speed for frequent rebuilds. Standard edition licensing suits multiple test VMs.
Documentation:
Download the HPE ProLiant Compute DL380 Gen12 6517P 1P 2x32GB-R 8SFF NS204i-u v2 MR408i-o 2x1000W PS NA Server Data sheet (.PDF)
Download the HPE ProLiant DL380 Gen12 Server Datasheet (.PDF)
Download the HPE ProLiant DL380 Gen12 Server Quick Specs (.PDF)
Intel and Intel Xeon are trademarks of Intel Corporation in the U.S. and other countries. All other third-party trademark(s) is/are property of their respective owner(s).
Pricing Notes:
- Pricing and product availability subject to change without notice.
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