New · Gen12 · SimpliVity 7.0

HPE SimpliVity 380 Gen12

A compact, scalable 2U hyperconverged building block that delivers integrated server, storage, and storage networking services. Now built on the HPE ProLiant Compute DL380 Gen12 with 6th Gen Intel® Xeon® processors and a choice of two hypervisors: HPE Morpheus VM Essentials or Broadcom VMware.

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Orderable now HPE SimpliVity Software 7.0 Part of HPE SimpliVity PC1000

HPE SimpliVity 380 Gen12 hyperconverged node — Built on the HPE ProLiant Compute DL380 Gen12 platform

Overview

Complete hyperconvergence in one 2U building block

HPE SimpliVity 380 delivers the agility and economics of the cloud with the control of on-premises IT. It combines compute, storage, and storage networking in a single, scalable node, with enterprise-grade management, protection, and performance for virtualized workloads at a fraction of the cost and complexity of traditional stacks.

The 380 Gen12 is the larger node in the HPE SimpliVity PC1000 family, built for consolidation.

Fully integrated system

x86 resources, storage, and storage networking in a single hyperconverged system, with orchestrated, simultaneous deployment and upgrades and less VM sprawl and over-provisioning.

Peak and predictable performance

An all-flash design delivers predictable, near-linear performance at near-wire speeds. Inline deduplication, compression, and optimization cut I/O and network traffic and shrink backup windows.

Scale in and scale out

Expand or shrink as needs change. Nodes at local and remote sites are managed as a single entity, and 1P nodes can take a second processor, more memory, and more storage in the field.

Lower TCO

Fewer discrete components to buy, guaranteed 10:1 data efficiency from HPE, and on-demand expansion to avoid over-provisioning for performance and capacity.

Predictive analytics with HPE InfoSight

Free with no license required: federation-, cluster-, and host-level capacity trends and predictions, automated wellness alerts and case creation, plus AHS and HPE iLO telemetry insights.

What's new

New on the Gen12 platform

HPE SimpliVity 380 moves to the HPE ProLiant Compute DL380 Gen12, with updated processors, memory, controller, management, and licensing, plus HPE SimpliVity Software 7.0.

7.0

HPE SimpliVity Software 7.0

Supports HPE Morpheus VM Essentials (HVM 9.0.2) and Broadcom VMware vSphere 8.0U3.

HPE StoreOnce integration
Stretch Cluster
Streamlined upgrade operations through HVM
HPE SimpliVity management plugin for VM Essentials Manager

NEW

6th Gen Intel Xeon

Granite Rapids processors from 16 to 86 cores, in 1- or 2-processor nodes.

NEW

DDR5-6400 memory

HPE DDR5-6400 Registered Smart Memory, from 192 GB to 8 TB per node.

NEW

MR416 storage controller

Broadcom-based HPE MR416i-o or MR416i-p controller with 8 GB cache, plus an NVMe boot device.

NEW

Term licensing by capacity

Socket-based 3- or 5-year term licenses, measured in usable capacity (TiB).

HPE iLO 7 Advanced remote management

Every node includes HPE Integrated Lights-Out (iLO) 7 Advanced for secure remote management, alongside hot-serviceable boot drives, redundant power supplies, and cluster expansion without downtime.

Hypervisor choice

VM Essentials or VMware, on the same node

Choose the hypervisor that fits your strategy when you order. Both run HPE SimpliVity Software 7.0 on the same Gen12 hardware.

	HPE Morpheus VM Essentials	Broadcom VMware
Software	HPE SimpliVity Software 7.0 with HPE Morpheus VM Essentials (HVM 9.0.2)	HPE SimpliVity Software 7.0 with VMware ESXi 8.0U3
Licensing	VM Essentials license is embedded in the HPE SimpliVity software license, on 3- or 5-year terms	vSphere and vCenter licenses procured from Broadcom or an authorized distributor (vSphere Foundation, Standard, or Essentials Plus Kit)
Management	VM Essentials Manager with the HPE SimpliVity management plugin, plus HPE InfoSight	VMware vCenter with the HPE SimpliVity management plugin, plus HPE InfoSight
Data protection	Built-in backup and restore, HPE StoreOnce integration, and Stretch Cluster	Built-in backup and restore, HPE StoreOnce integration with Data Immutability, HPE Backup Archive to HPE Cloud Bank Storage, and optional HPE SimpliVity RapidDR
Upgrades	Streamlined upgrade operations through HVM	Decoupled upgrades for ESXi-only updates with upgrade manager
Resiliency	Single disk resiliency (FTT1)	Single disk resiliency (FTT1)

HPE strongly recommends at least two nodes per cluster for high availability. A cluster supports up to 16 nodes and a federation up to 96, and a single federation cannot mix VM Essentials and VMware clusters.

Specifications

HPE SimpliVity 380 Gen12 at a glance

Platform: HPE ProLiant Compute DL380 Gen12
Form factor: 2U node; 3.44 x 26.75 x 17.54 in (8.73 x 67.94 x 44.54 cm)
Processors: 1 or 2 6th Gen Intel Xeon processors (Granite Rapids), 16 to 86 cores per processor, from the Xeon 6515P to the Xeon 6787P
Memory: HPE DDR5-6400 Registered Smart Memory in 32, 64, 96, 128, and 256 GB RDIMMs; 192 GB minimum, up to 8 TB per node
Boot device: HPE NS204i-u v2 960 GB NVMe hot-plug boot-optimized storage device (included)
Storage controller: HPE MR416i-o (OCP) or MR416i-p (PCIe) with 8 GB cache
Storage: 4 SAS Mixed Use SSDs plus 6 or 8 SAS Read Intensive SSDs, in 1.92 TB, 3.84 TB, 6.4 TB (MU), and 7.68 TB (RI) sizes; approximately 11 to 54 TiB usable
Resiliency: Single disk resiliency (FTT1)
Networking: OCP3 and PCIe Ethernet adapters from 1 Gb up to 200 Gb, depending on configuration
Fibre Channel: Optional HPE 32 Gb and 64 Gb Fibre Channel HBAs
GPU options: NVIDIA L4 24 GB, NVIDIA RTX A1000 8 GB, or NVIDIA L40S 48 GB
Power: Two redundant HPE Flex Slot power supplies, from 800 W Platinum to 1800-2200 W Titanium, plus 1600 W -48 VDC
Management: HPE iLO 7 Advanced, HPE InfoSight, and VM Essentials Manager or VMware vCenter
Warranty and support: 3-year parts, 3-year labor, 3-year onsite next business day; 3- or 5-year HPE SimpliVity 380 Gen12 solution support required

Storage

Usable capacity per node

Six all-flash configurations, each with four SAS Mixed Use SSDs and six or eight SAS Read Intensive SSDs. All are supported with both VM Essentials and VMware.

Usable capacity is approximate, after RAID and system overhead and before deduplication and compression. Final sizing comes from the HPE SimpliVity sizer.

4 x 1.92 + 6 x 1.92 TB10 SSDs

11 TiB

4 x 1.92 + 8 x 1.92 TB12 SSDs

13 TiB

4 x 3.84 + 6 x 3.84 TB10 SSDs

22 TiB

4 x 3.84 + 8 x 3.84 TB12 SSDs

28 TiB

4 x 6.4 + 6 x 7.68 TB10 SSDs

46 TiB

4 x 6.4 + 8 x 7.68 TB12 SSDs

54 TiB

Licensing

Simple, term-based licensing

Gen12 nodes move to socket-based term licenses measured by usable capacity, so software cost follows the capacity you deploy.

Term

3- or 5-year socket-based

Every node carries a socket-based term license that includes HPE SimpliVity software, HPE Morpheus VM Essentials software, and support.

Unit of measure

Usable capacity (TiB)

License quantity is based on the node's usable capacity, with Low and High capacity tiers. This applies to the Gen12 platform only.

Ordering

Added automatically

The configurator adds the right license for your processor count, capacity, and term. Broadcom VMware licenses are bought separately from Broadcom.

How to order

Five steps to a configured node

We build your HPE SimpliVity 380 Gen12 quote the same way HPE's configurator does.

Nodes and hypervisor

Choose the node quantity and VM Essentials or VMware.

License term

Select a 3- or 5-year software term.

Hardware options

Processors, memory, storage, networking, power, and GPUs.

Software license

The matching license is added automatically.

Service and support

Add 3- or 5-year solution support and HPE services.

Description	Part number
HPE SimpliVity 380 Gen12 EDSFF Configure-to-order Node	S8J33A
HPE SimpliVity FIO Software for VMware	S8K52A
HPE SimpliVity with Morpheus Software - essentials FIO Software	S8K53A

HPE SimpliVity Gen12 nodes can be ordered now, and HPE targeted general availability of the HPE SimpliVity 7.0 software for October 2026.

FAQ

Common questions

Need help sizing a cluster or choosing a hypervisor? A ServerComputeWorks specialist can help.

HPE SimpliVity 380 DatasheetPDF, October 2026 HPE SimpliVity 380 QuickSpecsConfiguration, options, and part numbers (PDF)

HPE SimpliVity 380 Gen12 is a compact, scalable 2U hyperconverged node built on the HPE ProLiant Compute DL380 Gen12. It delivers integrated server, storage, and storage networking services with 6th Gen Intel Xeon processors and a choice of HPE Morpheus VM Essentials or Broadcom VMware.

HPE SimpliVity 380 Gen12 supports HPE Morpheus VM Essentials, whose license is embedded in the HPE SimpliVity software license, or Broadcom VMware ESXi 8.0U3, with vSphere and vCenter licenses procured from Broadcom or an authorized distributor. A single federation cannot mix VM Essentials and VMware clusters.

Each node supports 192 GB to 8 TB of HPE DDR5-6400 Registered Smart Memory and approximately 11 to 54 TiB of usable all-flash capacity, using four SAS Mixed Use SSDs plus six or eight SAS Read Intensive SSDs, before deduplication and compression.

Every node has a socket-based term license for 3 or 5 years that includes HPE SimpliVity software, HPE Morpheus VM Essentials software, and support. On Gen12, usable capacity in TiB is the standard unit of measure, and the configurator adds the matching license automatically.

HPE strongly recommends a minimum of two nodes per cluster for high availability. A single cluster supports up to 16 nodes and a single federation supports up to 96 nodes.