HPE ProLiant ML350 Gen12 6515P Server
16-Core, 2.40 GHz, 64GB RAM
Fast Delivery
Pre-Configured
Ships Immediately
Quick Specs:
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Overview:
Are you looking for our most flexible and powerful tower server for your SMB and remote offices?
The HPE ProLiant Compute ML350 Gen12 is a robust 2P tower server with optional rackable chassis for various environments, and delivers exceptional compute performance, security, reliability, and expandability.
Powered by latest Intel® Xeon® 6700/6500 P-series processors (up to 86 Pcores per socket), up to 8 TB DDR5 6400 memory, the HPE ProLiant Compute ML350 Gen12 server fulfills a wide range of demanding workloads.
The silicon root of trust anchors the server firmware to an HPE-exclusive ASIC, creating a fingerprint for the Intel® Xeon® 6700/6500 P-series processors that must be matched exactly before the server will boot.
The HPE ProLiant Compute ML350 Gen12 server is an excellent choice for diverse workloads such as IT infrastructure, data management, VDI, and ERP/CRM. Scale and adapt to any environment with this server and accelerate your growing business.
P87788-005 - HPE ProLiant Compute ML350 Gen12 server with one Intel® Xeon® 6515P Processor, 64 GB (1x64 GB) Dual Rank Memory, one HPE MR408i-o Gen12 x8 Lanes 4GB Cache OCP SPDM Storage Controller, support for eight SFF drives, three standard fans, two HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSDs, two HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kits, one TPM (Trusted Platform Module), one HPE ProLiant Compute ML Gen12/Gen12 Intrusion Cable Kit, and a 3/3/3 warranty
What's New
- Powered by Intel® Xeon® 6700 and 6500 series with P-cores; up to 86 P-cores per socket (172 P-cores per server), 350W (TDP); increased memory bandwidth to 6400 MT/s2, up to 8TB DDR5 memory capacity.
- Supports ultra-high SSD performance with NVMe x4 and EDSFF drive cages, and allowing mixed dual-mode LFF and tri-mode SFF drive cages as hybrid storage optimization solution.
- Provides up to 24 NVMe drives with PCIe Gen5 x2 bandwidth to have maximum storage capacity with balanced performance solution.
- Includes HPE Integrated Lights-Out 7 (iLO 7) server management software that enables you to securely configure, monitor, and update your HPE ProLiant Compute Gen12 servers seamlessly from anywhere.
- Supports new NS204i-u V2 as hot-pluggable, high-availability, RAID1-protected M.2 NVMe boot option.
- Supports NVIDIA® L4 24GB Accelerator.
Features:
Next-Level Security, Chip to Cloud
From silicon to software, from factory to cloud, and from generation to generation, HPE ProLiant Compute Gen12 is engineered with a fundamental security approach to defend against increasingly complex threats through an uncompromising commitment to constant security advancements.
Silicon root of trust from HPE, establishes a zero-trust security framework at the silicon level to ensure firmware integrity. Continuous protection detects compromised servers and prevents them from booting if malicious code is found. Edge servers are safeguarded with default IDevID certificates.
HPE ProLiant Compute servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.
Intel® Xeon® 6 processors add hardware- and software-assisted security features such as Intel® Software Guard Extensions (SGX) for application isolation and Trusted Domain Extensions (TDX) for VM Isolation, which help protect the server hardware foundation and safeguard data in memory.
HPE iLO 7 supports quantum-resistant (PQC) algorithms and signs HPE ProLiant Compute Gen12 firmware with algorithms approved by CNSA 2.0, which enhances resilience against potential future attacks by quantum computers.
Optimized Performance for your Workloads: Accelerated, Open, and Efficient
The HPE ProLiant Compute ML350 Gen12 server is an excellent choice for compute and data storage demanding workloads (AI, machine learning [ML], telco, DB analytics,) requiring high core count, GPU capabilities, and network and I/O bandwidth.
Harness major compute performance. The HPE ProLiant Compute ML350 Gen12 server is powered by Intel® Xeon® 6700P/6500P-series processors that support up to 86 P-cores (172 P-cores per server) at 350W TDP.
Enjoy advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 4 x16 PCIe Gen5 and 2 x16 OCP slots to improve I/O throughput and reduce latency.
Utilize 32 DIMM slots for up to 8 TB DDR5 memory with increased memory bandwidth and performance.
Intuitive Cloud Operating Experience: Simple, Self-service, and Automated
HPE ProLiant Compute ML350 Gen12 servers are engineered for your hybrid world. The new HPE ProLiant Compute Gen12 servers simplify the way you control your business’s compute—from edge to cloud—with a cloud operating experience.
Transform business operations and pivot your team from reactive to proactive with global visibility and insight through a self-service console.
Automate tasks for efficiency in deployment, instant scalability, and seamless, simplified support and lifecycle management reducing tasks and shortening maintenance windows.
These experiences are engineered and built into all HPE ProLiant Compute Gen12 servers, whether purchased as physical servers or consumed as-a-service using HPE GreenLake as your compute and storage demands grow.
Industry-leading Services and Ease of Deployment
The HPE ProLiant Compute ML350 Gen12 server comes with a complete set of HPE Services, delivering confidence, reducing risk, and helping customers realize agility and stability.
HPE Services simplify all stages of the IT journey. Advisory and Transformation Services professionals understand your challenges and design an effective solution. Professional Services enable rapid deployment of solutions and Operational Services provide ongoing support.
Services provided under Operational Services include: HPE Flexible Capacity, HPE Datacenter Care, HPE Infrastructure Automation, HPE Campus Care, HPE Proactive Services and multi-vendor coverage.
HPE IT investment solutions help you transform into a digital business with IT economics that align with your business goals. Benefit from real-time operational feedback on server performance plus recommendations for fine-tuning BIOS settings to customize for changing business needs.
Technical Specifications:
| HPE ProLiant Compute ML350 Gen12 6515P 16c 1P 1x64GB-R 8SFF MR408i-o 2x480GB SSD 2x800W PS NA Server Specifications | |
|---|---|
| Product Number | P87788-005 |
| Processor name | Intel® Xeon® 6515P (16 core, 2.40 GHz, 72 MB L3, 150W) |
| Processor number | 1 processor included |
| Processor core available | 16 core |
| Processor cache | 72 MB L3 |
| Processor speed | 2.40 GHz |
| Memory type | HPE DDR5 Smart Memory |
| Included memory | 64 GB (1x64 GB, 6400 MT/s) |
| System fan features | 3x Standard Fans |
| Expansion slots | Up to 10[1] PCIe Gen5 and 2 OCP slots. Refer to the QuickSpecs for more detail. |
| Form factor | 4U Tower |
| Network controller | Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE |
| Storage controller | HPE MR408i-o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller |
| Included drives | 2x HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSD |
| Optical drive type | Optional DVD-ROM or DVD-RW. Refer to the QuickSpecs for more detail. |
| Power supply type | 2x HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit |
| Infrastructure management | HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE OneView Advanced (require licenses), and HPE Compute Ops Management (optional subscription available). |
| Security | UEFI Secure Boot and Secure Start support. Intel® Software Guard Extensions (SGX) support. Immutable Silicon Root of Trust. TPM (Trusted Platform Module) 2.0 support. Front bezel key-lock feature, Intrusion Cable (Optional), Padlock slot and Kensington Lock slot support. |
| Warranty | Server Warranty includes three years of parts, three years of labor, and three years of on-site support coverage. |
Hardware Specs:
HPE ProLiant ML350 Gen12 server
Front View – Chassis with optional 12 EDSFF/8 SFF/4 LFF Drive Cage Kits and front NS204i-u shown
| 1 | DisplayPort 1.1a |
| 2 | USB 3.2 Gen1 port |
| 3 | iLO service port (Type-C) |
| 4 | UID button/LED |
| 5 | OCP NIC status LED1 |
| 6 | Health LED |
| 7 | Power on/Standby button and system power LED |
| 8 | Optical drive bay |
| 9 | NS204i-u (Front) or Media Bay filler panel/LTO |
| 10 | Serial number/iLO information pull tab |
| 11 | Box 3: 12 EDSFF drive cage, Optional for 8SFF/4LFF/NVMex4*/EDSFF |
| 12 | Box 2: 8 SFF drive cage, Optional for 8SFF/4LFF/NVMex4* |
| 13 | Box 1: 4 LFF drive cage, Optional for 8SFF/4LFF/NVMex4* with x2 cable kit or Internal LTO Tape Drive |
1x4 SFF drive cage supports NVMe drives only. Up to (2) NVMex4 drive cage with x4 DA cable kit or (3) NVMEx4 drive cage with x2 DA cable kit.
Rear View – With optional rear NS204i-u and HPE Flex Slot RPS shown.
| 1 | HPE NS204i-u V2 (Optional) |
| 2 | PCIe Slots 9-10 (Optional tertiary riser, 2nd processor required for expansion card installation) |
| 3 | Flexible Slot power supply 1 |
| 4 | Flexible Slot power supply 2 (Optional) |
| 5 | VGA Port |
| 6 | External Fan connector 9 |
| 7 | Slot 15 OCP B (Optional for NIC) |
| 8 | Serial port (Optional) |
| 9 | iLO management port |
| 10 | USB 3.2 Gen 1 ports x2 |
| 11 | External Fan connector 10 |
| 12 | Slot 14 OCP A (Optional for OROC/NIC) |
| 13 | PCIe Slots 1-4 (Primary riser) |
| 14 | Padlock eye |
| 15 | PCIe Slots 5-8 (Optional Secondary riser, 2nd processor required for expansion card installation) |
| 16 | Kensington slot |
Internal View – with optional 2nd CPU, OCP NIC adapter and NS204i-u shown
| 1 | CPU Socket 11 |
| 2 | CPU Socket 22 |
| 3 | (2) USB 3.2 Gen1 ports |
| 4 | Secondary riser connector (Optional) |
| 5 | Megacell battery holder (Under)/ HPE NS204i-u V2 (Upper) |
| 6 | HPE NS204i-u V2 power connector |
| 7 | Tertiary riser* sideband connector (Optional) |
| 8 | Serial port cable connector |
| 9 | Slot 15 OCP B (Optional for NIC adapter) |
| 10 | Primary riser connector |
| 11 | Slot 14 OCP A (Optional for OROC/NIC) |
1 CPU1 (bottom) shown Performance Heatsink with fully memory populated in 16 slots (32 slots in total)
2 CPU2 (top) shown Performance Heatsink with fully memory populated in 16 slots (32 slots in total)
Services & Add-Ons:
HPE Tech Care (Support Plans)
HPE Tech Care is an operational support service from HPE for hardware, software, and multivendor systems. It helps your systems run smoothly, improves reliability, and drives performance. Official HPE Tech Care Datasheet
- Hardware & software support from HPE experts
- Access via phone, email, chat & self-service tools
- Standard response times & on-site as per HPE availability
- General technical guidance for operations & management
- All features in Basic, plus faster response & support
- Enhanced phone response; quicker callback for severity-1 incidents
- Proactive technical guidance and more frequent advisory from HPE
- Self-serve tools and knowledge base + access to digital insights via HPE
| Feature | Basic | Essential |
|---|---|---|
| Hardware & Software Coverage | HPE-provided support for both hardware & software | Same, with faster response & enhanced assistance |
| Support Channels | Phone, email, chat, self-service tools | All channels + more aggressive response SLAs |
| Response Time | Standard response per HPE’s availability | Improved/faster response for high-severity issues (e.g. severity-1) |
| Proactive Guidance | General technical guidance | Extra guidance in usage, management, and performance opportunities |
HPE iLO Advanced (Remote Management)
HPE Integrated Lights-Out (iLO) Advanced unlocks secure, full-feature remote administration for HPE ProLiant servers—enabling setup, monitoring, troubleshooting, and power control from anywhere.
Key Capabilities
- Integrated Remote Console with virtual keyboard and mouse
- Virtual media & folders for remote OS/software installs
- Console record & playback for audit and troubleshooting
- Collaborative access for multiple administrators
- Power/thermal monitoring with history and dynamic capping
- iLO Federation group management (group media, power, licensing)
Security & Compliance
- Silicon Root of Trust and platform component integrity checks
- Directory integration and 2-factor authentication (CAC/PIV)
- Device identity (IDevID/LDevID) aligned with IEEE 802.1AR
- Kerberos-based single sign-on for streamlined access
| Feature | iLO Standard | iLO Advanced |
|---|---|---|
| Remote Console | Basic access | Full Integrated Remote Console with collaboration |
| Virtual Media | Limited | Virtual media & folders for remote installs |
| Recording | — | Console record & playback |
| Power & Thermal | Monitoring | Monitoring + history and dynamic power capping |
| Federation (Group Mgmt) | Limited | Group media, power control, power capping, license activation |
| Security | Baseline iLO security | Directory auth, CAC/PIV, Kerberos, device identities, silicon root of trust enhancements |
Microsoft Windows Server 2025 (ROK AMS Software)
Choose the right edition of Microsoft Windows Server 2025 to power your Smart Choice Servers and Storage. Each edition is tailored to different business sizes and virtualization needs.
Essentials10-Core
- Up to 25 users / 50 devices
- Simplified licensing for small businesses
- No virtualization rights
Standard16-Core
- For growing businesses
- Supports 2 virtual machines
- Full Windows Server feature set
Datacenter16-Core
- For enterprises & data centers
- Unlimited virtualization rights
- Advanced features for large-scale workloads
| Edition | Best For | Virtualization | Users / Devices |
|---|---|---|---|
| Essentials | Small businesses | None | 25 users / 50 devices |
| Standard | SMBs with moderate workloads | Up to 2 VMs | Licensed per 16-core base + CALs |
| Datacenter | Enterprises / virtualization-heavy environments | Unlimited VMs | Licensed per 16-core base + CALs |
HPE Storage Options
Choose the right storage for your Smart Choice Servers. HPE offers HDD, SSD, and SAS options, each with different balances of cost, performance, and reliability.
HDD Hard Disk Drive
- Large capacity, lower cost
- Slower performance
- Great for bulk storage & backups
SSD Solid-State Drive
- High performance, faster boot & apps
- Better for databases & OS
- Higher cost per GB
SAS Serial Attached SCSI
- Enterprise-grade reliability
- High performance for mission-critical workloads
- Designed for 24/7 operations
| Type | Best For | Performance | Cost |
|---|---|---|---|
| HDD | Bulk storage, backups | Slowest | Low |
| SSD | OS, applications, databases | High | Medium–High |
| SAS | Enterprise workloads, 24/7 uptime | Very High | High |
HPE Memory Options
Smart Choice Servers and Storage support DDR5 memory for improved performance, efficiency, and scalability. Choosing the right amount of memory ensures your workloads run smoothly, whether it’s databases, virtualization, or everyday applications.
16GB DDR5-4800
- Good for basic workloads & file servers
- Suitable for small office environments
- Entry-level performance
32GB DDR5-4800
- Ideal for virtualization, databases, and multitasking
- Supports more demanding business workloads
- Higher performance headroom
| Option | Best For | Performance | Scalability |
|---|---|---|---|
| 16GB DDR5-4800 | Entry workloads, file/print servers | Baseline | Limited |
| 32GB DDR5-4800 | Virtualization, databases, larger workloads | High | Better scalability with more DIMMs |
Quick Recommendations
To help you decide, we’ve put together sample configurations that match common business needs.
Small Office / Basic Workloads
- Support: Tech Care Basic (3Y)
- Remote Mgmt: Optional iLO Advanced
- OS: Windows Server 2025 Essentials
- Storage: HDD (affordable, large capacity)
- Memory: 16GB DDR5
Why: Essentials edition is perfect for ≤25 users, while 16GB RAM and HDDs keep costs low. iLO Advanced is optional if you don’t need remote management.
Growing Business / Virtualization
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced (3Y)
- OS: Windows Server 2025 Standard
- Storage: SSD (OS/apps) + HDD (data)
- Memory: 32GB DDR5
Why: Standard edition allows up to 2 VMs for growth. A mix of SSD + HDD balances performance and cost. iLO Advanced ensures remote management as IT expands.
Enterprise / Mission-Critical Workloads
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced with Federation
- OS: Windows Server 2025 Datacenter
- Storage: SAS drives (high reliability)
- Memory: 32GB+ DDR5 (expandable)
Why: Datacenter edition unlocks unlimited virtualization. SAS drives support 24/7 uptime, while more RAM ensures smooth performance across many workloads.
Branch Office / Remote Site
- Support: Tech Care Essential (3Y)
- Remote Mgmt: iLO Advanced (critical for remote access)
- OS: Windows Server 2025 Standard
- Storage: SSD for fast apps, small HDD for data
- Memory: 16GB or 32GB DDR5
Why: Remote management via iLO is vital since IT staff may not be on-site. Standard edition supports light virtualization or file/print roles for branch users.
Development / Test Lab
- Support: Tech Care Basic (1–3Y)
- Remote Mgmt: iLO Advanced (collaboration features)
- OS: Windows Server 2025 Standard
- Storage: SSD-heavy (fast rebuilds)
- Memory: 32GB DDR5
Why: Developers benefit from iLO’s remote console recording/playback and SSD speed for frequent rebuilds. Standard edition licensing suits multiple test VMs.
Documentation:
Download the HPE ProLiant Compute ML350 Gen12 6515P 16c 1P 1x64GB-R 8SFF MR408i-o 2x480GB SSD 2x800W PS NA Server Data sheet (.PDF)
Download the HPE ProLiant ML350 Gen12 server Datasheet (.PDF)
Download the HPE ProLiant ML350 Gen12 server Quick Specs (.PDF)
Notes:
Intel and Intel Xeon are trademarks of Intel Corporation in the U.S. and other countries.
NVIDIA is a trademark and/or registered trademark of NVIDIA Corporation in the U.S. and other countries.
All third-party marks are property of their respective owners.
Tertiary riser kit to support Slot 9/10 with PCIe Gen5 will be available in Q2, 2025.
The maximum memory speed is a function of the memory type, memory configuration, and processor model.
Pricing Notes:
- Pricing and product availability subject to change without notice.
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