HPE ProLiant ML350 Gen11 4510 Server
12-Core 2.4GHz 32GB RAM
Our Price: $7,596.00
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Overview:
Are you looking for a robust and flexible tower optimized server for your SMB and remote offices?
The HPE ProLiant ML350 Gen11 is a powerful 2P tower server with optional rackable chassis for various environments, and delivers exceptional compute performance, security, reliability, and expandability.
Powered by 4th and 5th Gen Intel® Xeon® Scalable Processors up to 64 cores1, up to 8 TB DDR5, PCIe Gen5, enhanced I/O and GPU support, and EDSFF storage, the HPE ProLiant ML350 Gen11 server fulfills a wide range of demanding workloads.
The silicon root of trust anchors the server firmware to an HPE-exclusive ASIC, creating a fingerprint for the 4th and 5th Gen Intel Xeon Scalable processors that must be matched exactly before the server will boot.
The HPE ProLiant ML350 Gen11 server is an excellent choice for diverse workloads such as IT infrastructure, Data Management, VDI, ERP/CRM. Scale and adapt to any environment with this server and accelerate your growing business.
What's New
- Powered by 4th and 5th Gen Intel® Xeon® Scalable Processors that support up to 64 cores1 (128 cores per server), 350W TDP.
- Increased memory bandwidth to 5600 MT/s2, performance and lower power requirements with up to 8 TB DDR5 memory capacity with 32 DIMM slots.
- Advanced data transfer rates from the PCIe Gen5 serial expansion bus, support up to 10 standard PCIe Gen5 slots and 2 OCP 3.0 slots3.
- Includes HPE Integrated Lights-Out 6 (iLO 6) server management software that enables you to securely configure, monitor, and update your HPE ProLiant Gen11 servers seamlessly from anywhere.
- Supports hot-pluggable, high-availability, RAID1 protected M.2 NVMe boot option.
- Supports new EDSFF E3.S NVMe form factor to enable higher-density servers and storage systems, optimization of PCIe lanes from CPUs, and ultra-high SSD performance.
Notes:
1Support up to 64-core with 5th Gen Intel processor and 60-core with 4th Gen Intel processor
2DDR5 5600 MT/s memory is limited to support with 5th Gen Intel processors. The maximum memory speed is a function of the memory type, memory configuration, and processor model.
3OCP and two tertiary riser PCIe slots are shared with 3 internal MICO connectors.
Features:
Intuitive Cloud Operating Experience: Simple, Self-service, and Automated
HPE ProLiant ML350 Gen11 servers are engineered for your hybrid world. The new ProLiant Gen11 servers simplify the way you control your business’s compute—from edge to cloud—with a cloud operating experience.
Transform business operations and pivot your team from reactive to proactive with global visibility and insight through a self-service console.
Automate tasks for efficiency in deployment, instant scalability, and seamless, simplified support and lifecycle management reducing tasks and shortening maintenance windows.
These experiences are engineered and built into all HPE ProLiant Gen11 servers, whether purchased as physical servers or consume as-a-service using HPE GreenLake as your compute and storage demands grow.
Simplify and secure server management from edge to cloud with HPE GreenLake for Compute Ops Management. HPE GreenLake for Compute Ops Management is an as-a-service compute management experience that delivers greater simplicity, agility, and speed across your entire compute landscape, globally.
Trusted Security by Design: Uncompromising, Fundamental, and Protected
HPE ProLiant ML350 Gen11 server uses the silicon root of trust to anchor the firmware of an HPE ASIC, creating an immutable fingerprint for the Intel Processor that must be matched exactly before the server will boot. This verifies that malicious code is contained, and healthy servers are protected.
HPE ProLiant Gen11 servers continuously protect healthy servers at the edge by providing rapid detection of security-compromised servers, even to the point of not allowing them to boot if it identifies and contains malicious code, with IDevID certificates installed by default.
HPE ProLiant Gen11 servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of the operating system, application, data connections, and providing a fast path to bring a server back online and into normal operations.
From silicon to software, from factory to cloud, and from generation to generation, HPE ProLiant Gen11 is engineered with a fundamental security approach to defend against increasingly complex threats through an uncompromising commitment to constant security advancements that are built into our DNA.
Optimized Performance for your Workloads: Accelerated, Open, and Efficient
The HPE ProLiant ML350 Gen11 server is an excellent choice for Compute and data storage demanding workloads (AI, ML, telco, DB analytics,) requiring high core count, GPU capabilities, and network and I/O bandwidth.
Harness major compute performance. The HPE ProLiant ML350 Gen11 server is powered by 4th and 5th Gen Intel® Xeon® Scalable Processors that support up to 64 cores1 (128 cores per server) at 350W TDP.
Enjoy advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 4 x16 PCIe Gen5 and 2 x16 OCP slots to improve I/O throughput and reduce latency.
Utilize 32 DIMM channels for up to 8 TB DDR5 memory with increased memory bandwidth and performance, and lower power requirements.
Industry-leading Services and Ease of Deployment
The HPE ProLiant ML350 Gen11 server comes with a complete set of HPE Services, delivering confidence, reducing risk, and helping customers realize agility and stability.
HPE Services simplify all stages of the IT journey. Advisory and Transformation Services professionals understand customer challenges and design an effective solution. Professional Services enable rapid deployment of solutions and Operational Services provide ongoing support.
Services provided under Operational Services include: HPE Flexible Capacity, HPE Datacenter Care, HPE Infrastructure Automation, HPE Campus Care, HPE Proactive Services and multi-vendor coverage.
HPE IT investment solutions help you transform to a digital business with IT economics that align to your business goals.
Benefit from real-time operational feedback on server performance plus recommendations for fine-tuning BIOS settings to customize for changing business needs.
Technical Specifications:
| HPE ProLiant ML350 Gen11 4510 2.4GHz 12c 1P 1x32GB-R 4LFF MR408i-o 2x8TB HDD 2x800W PS NA Server Specifications | |
|---|---|
| Detailed product description | HPE ProLiant ML350 Gen11 server with one Intel® Xeon® Silver 4510 Processor, 32 GB (1x32 GB) Dual Rank Memory, one HPE MR408i-o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller, support for four LFF drives, three standard fans, two HPE 8TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty 512e Multi Vendor HDDs, two HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kits, and a 3/3/3 warranty |
| Product Number | P87112-005 |
| Processor name | Intel® Xeon® Silver 4510 (12 core, 2.40 GHz, 30 MB L3, 150W) |
| Processor number | 1 processor included |
| Processor core available | 12 core |
| Processor cache | 30 MB L3 |
| Processor speed | 2.40 GHz |
| Memory type | HPE DDR5 Smart Memory |
| Included Memory | 32 GB (1x32 GB, 5600 MT/s) |
| Accelerators | Optional: Supports NVIDIA L40/A16/L4/RTX 4000 Ada Graphics Accelerator for HPE, pending configuration |
| System fan features | 3x Standard Fans |
| Expansion slots | 2 to 10 PCIe Gen5 (2 OCP 3.0). Refer to the QuickSpecs for more detail. |
| Form factor | 4U Tower |
| Network controller | Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE |
| Storage controller | HPE MR408i-o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller |
| Included drives | 2x HPE 8TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty 512e Multi Vendor HDD |
| Optical drive type | Optional DVD-ROM or DVD-RW. Optional Half-Height RDX, up to 1. Refer to the QuickSpecs for more detail. |
| Power supply type | 2x HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit |
| Infrastructure management | HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE OneView Advanced (require licenses), and HPE Compute Ops Management. |
| Security | UEFI Secure Boot and Secure Start support. Intel® Software Guard Extensions (SGX) support. Immutable Silicon Root of Trust. TPM (Trusted Platform Module) 2.0 support. Front bezel key-lock feature, Intrusion Cable (Optional), Padlock slot and Kensington Lock slot support. |
| Warranty | 3/3/3: Server Warranty includes three years of parts, three years of labor, and three years of on-site support coverage. |
| Weight | 49.13 kg (108.313 lb) |
| Dimensions | 30.48 x 58.42 x 98.43 cm (12 x 23 x 38.75 in) |
Hardware Specs:
HPE ProLiant ML350 Gen11 server

Front View – LFF chassis with optional Gen11 4LFF HDD Cage Kits shown (Rack mode)
| 1 | Optical drive bay |
| 2 | Media bay filler panel |
| 3 | Serial number/iLO information pull tab |
| 4 | Box 3: Default drive cage for 4LFF |
| 5 | Box2: Optional drive cage for 8SFF/4LFF |
| 6 | Box1: Optional drive cage for 8SFF/4LFF, or USB RDX docking station. |
| 7 | DisplayPort 1.1a |
| 8 | USB 3.2 Gen1 port |
| 9 | iLO service port |
| 10 | UID button/LED |
| 11 | NIC status LED |
| 12 | Health LED |
| 13 | Power on/Standby button and system power LED |

Front View – SFF chassis with optional Gen11 8SFF HDD Cage Kits shown (Tower mode)
| 1 | DisplayPort 1.1a |
| 2 | USB 3.2 Gen1 port |
| 3 | iLO service port |
| 4 | UID button/LED |
| 5 | NIC status LED |
| 6 | Health LED |
| 7 | Power on/Standby button and system power LED |
| 8 | Optical drive bay |
| 9 | Media bay filler panel |
| 10 | Serial number/iLO information pull tab |
| 11 | Box1: Optional drive cage for 8SFF |
| 12 | Box2: Optional drive cage for 8SFF |
| 13 | Box 3: Default drive cage for 8SFF |
Notes:
- For NHP LFF chassis, please find detail in the ML350 Gen10 User Guide.
- Image shown without the security front bezel which is standard in every ML350 Gen10 unit.

Internal View – with optional 2nd CPU, OCP NIC adapter and NS204i-u shown
| 1 | CPU Socket 11 & 22 |
| 2 | Dual USB port (Stacked, Top: USB 3.2 Gen1 port, Bottom: USB 2.0 port) |
| 3 | Megacell battery holder (Under) |
| 4 | HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional) |
| 5 | Secondary riser connector |
| 6 | Tertiary riser sideband connector |
| 7 | Serial port cable connector |
| 8 | Slot 15 OCP 2 (Optional for NIC adapter) |
| 9 | HPE NS204i-u power connector |
| 10 | Primary riser connector |
| 11 | Slot 14 OCP 1 (Optional for OROC/NIC adapter) |

Rear View – With HPE Flex Slot RPS shown.
| 1 | Kensington security slot |
| 2 | PCIe Slots 9-10 (Optional tertiary riser, 2nd processor required) |
| 3 | Flexible Slot power supply 1 |
| 4 | Flexible Slot power supply 2 (Optional) |
| 5 | VGA Port |
| 7 | Serial port (Optional) |
| 8 | iLO management port |
| 9 | USB 3.2 Gen 1 ports x2 |
| 10 | Slot 14 OCP 1 (Optional for OROC/NIC adapter) |
| 11 | PCIe Slots 1-4 (Primary riser) |
| 12 | Padlock eye |
| 14 | HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional) |
Services & Add-Ons:
HPE Tech Care (Support Plans)
HPE Tech Care is an operational support service from HPE for hardware, software, and multivendor systems. It helps your systems run smoothly, improves reliability, and drives performance. Official HPE Tech Care Datasheet
- Hardware & software support from HPE experts
- Access via phone, email, chat & self-service tools
- Standard response times & on-site as per HPE availability
- General technical guidance for operations & management
- All features in Basic, plus faster response & support
- Enhanced phone response; quicker callback for severity-1 incidents
- Proactive technical guidance and more frequent advisory from HPE
- Self-serve tools and knowledge base + access to digital insights via HPE
| Feature | Basic | Essential |
|---|---|---|
| Hardware & Software Coverage | HPE-provided support for both hardware & software | Same, with faster response & enhanced assistance |
| Support Channels | Phone, email, chat, self-service tools | All channels + more aggressive response SLAs |
| Response Time | Standard response per HPE’s availability | Improved/faster response for high-severity issues (e.g. severity-1) |
| Proactive Guidance | General technical guidance | Extra guidance in usage, management, and performance opportunities |
HPE iLO Advanced (Remote Management)
HPE Integrated Lights-Out (iLO) Advanced unlocks secure, full-feature remote administration for HPE ProLiant servers—enabling setup, monitoring, troubleshooting, and power control from anywhere.
Key Capabilities
- Integrated Remote Console with virtual keyboard and mouse
- Virtual media & folders for remote OS/software installs
- Console record & playback for audit and troubleshooting
- Collaborative access for multiple administrators
- Power/thermal monitoring with history and dynamic capping
- iLO Federation group management (group media, power, licensing)
Security & Compliance
- Silicon Root of Trust and platform component integrity checks
- Directory integration and 2-factor authentication (CAC/PIV)
- Device identity (IDevID/LDevID) aligned with IEEE 802.1AR
- Kerberos-based single sign-on for streamlined access
| Feature | iLO Standard | iLO Advanced |
|---|---|---|
| Remote Console | Basic access | Full Integrated Remote Console with collaboration |
| Virtual Media | Limited | Virtual media & folders for remote installs |
| Recording | — | Console record & playback |
| Power & Thermal | Monitoring | Monitoring + history and dynamic power capping |
| Federation (Group Mgmt) | Limited | Group media, power control, power capping, license activation |
| Security | Baseline iLO security | Directory auth, CAC/PIV, Kerberos, device identities, silicon root of trust enhancements |
Microsoft Windows Server 2025 (ROK AMS Software)
Choose the right edition of Microsoft Windows Server 2025 to power your Smart Choice Servers and Storage. Each edition is tailored to different business sizes and virtualization needs.
Essentials10-Core
- Up to 25 users / 50 devices
- Simplified licensing for small businesses
- No virtualization rights
Standard16-Core
- For growing businesses
- Supports 2 virtual machines
- Full Windows Server feature set
Datacenter16-Core
- For enterprises & data centers
- Unlimited virtualization rights
- Advanced features for large-scale workloads
| Edition | Best For | Virtualization | Users / Devices |
|---|---|---|---|
| Essentials | Small businesses | None | 25 users / 50 devices |
| Standard | SMBs with moderate workloads | Up to 2 VMs | Licensed per 16-core base + CALs |
| Datacenter | Enterprises / virtualization-heavy environments | Unlimited VMs | Licensed per 16-core base + CALs |
HPE Storage Options
Choose the right storage for your Smart Choice Servers. HPE offers HDD, SSD, and SAS options, each with different balances of cost, performance, and reliability.
HDD Hard Disk Drive
- Large capacity, lower cost
- Slower performance
- Great for bulk storage & backups
SSD Solid-State Drive
- High performance, faster boot & apps
- Better for databases & OS
- Higher cost per GB
SAS Serial Attached SCSI
- Enterprise-grade reliability
- High performance for mission-critical workloads
- Designed for 24/7 operations
| Type | Best For | Performance | Cost |
|---|---|---|---|
| HDD | Bulk storage, backups | Slowest | Low |
| SSD | OS, applications, databases | High | Medium–High |
| SAS | Enterprise workloads, 24/7 uptime | Very High | High |
HPE Memory Options
Smart Choice Servers and Storage support DDR5 memory for improved performance, efficiency, and scalability. Choosing the right amount of memory ensures your workloads run smoothly, whether it’s databases, virtualization, or everyday applications.
16GB DDR5-4800
- Good for basic workloads & file servers
- Suitable for small office environments
- Entry-level performance
32GB DDR5-4800
- Ideal for virtualization, databases, and multitasking
- Supports more demanding business workloads
- Higher performance headroom
| Option | Best For | Performance | Scalability |
|---|---|---|---|
| 16GB DDR5-4800 | Entry workloads, file/print servers | Baseline | Limited |
| 32GB DDR5-4800 | Virtualization, databases, larger workloads | High | Better scalability with more DIMMs |
Quick Recommendations
To help you decide, we’ve put together sample configurations that match common business needs.
Small Office / Basic Workloads
- Support: Tech Care Basic (3Y)
- Remote Mgmt: Optional iLO Advanced
- OS: Windows Server 2025 Essentials
- Storage: HDD (affordable, large capacity)
- Memory: 16GB DDR5
Why: Essentials edition is perfect for ≤25 users, while 16GB RAM and HDDs keep costs low. iLO Advanced is optional if you don’t need remote management.
Growing Business / Virtualization
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced (3Y)
- OS: Windows Server 2025 Standard
- Storage: SSD (OS/apps) + HDD (data)
- Memory: 32GB DDR5
Why: Standard edition allows up to 2 VMs for growth. A mix of SSD + HDD balances performance and cost. iLO Advanced ensures remote management as IT expands.
Enterprise / Mission-Critical Workloads
- Support: Tech Care Essential (5Y)
- Remote Mgmt: iLO Advanced with Federation
- OS: Windows Server 2025 Datacenter
- Storage: SAS drives (high reliability)
- Memory: 32GB+ DDR5 (expandable)
Why: Datacenter edition unlocks unlimited virtualization. SAS drives support 24/7 uptime, while more RAM ensures smooth performance across many workloads.
Branch Office / Remote Site
- Support: Tech Care Essential (3Y)
- Remote Mgmt: iLO Advanced (critical for remote access)
- OS: Windows Server 2025 Standard
- Storage: SSD for fast apps, small HDD for data
- Memory: 16GB or 32GB DDR5
Why: Remote management via iLO is vital since IT staff may not be on-site. Standard edition supports light virtualization or file/print roles for branch users.
Development / Test Lab
- Support: Tech Care Basic (1–3Y)
- Remote Mgmt: iLO Advanced (collaboration features)
- OS: Windows Server 2025 Standard
- Storage: SSD-heavy (fast rebuilds)
- Memory: 32GB DDR5
Why: Developers benefit from iLO’s remote console recording/playback and SSD speed for frequent rebuilds. Standard edition licensing suits multiple test VMs.
Documentation:
Download the HPE ProLiant ML350 Gen11 4510 2.4GHz 12c 1P 1x32GB-R 4LFF MR408i-o 2x8TB HDD 2x800W PS NA Server Data sheet (.PDF)
Download the HPE ProLiant ML350 Gen11 server Datasheet (.PDF)
Download the HPE ProLiant ML350 Gen11 server Quick Specs (.PDF)
*Intel and Intel Xeon are trademarks of Intel Corporation in the U.S. and other countries. All other third-party trademark(s) is/are property of their respective owner(s).
Pricing Notes:
- Pricing and product availability subject to change without notice.
Our Price: $7,596.00
